- Seeded teams, on the right of each fixture, are at home in the second legs.
- Matches take place on 14 and 21 February except:
first leg of Fenerbahçe v Zenit on Tuesday 12 February at 18:55CET;
second leg of Sevilla v Lazio on Wednesday 20 February at 18:00CET.
Lazio v Sevilla
Lazio (ITA)
UEFA ranking: 39
Domestic position: 5
Group stage: W3 D0 L3 F9 A11
Last season: UEFA Europa League quarter-finals (lost 6-5 v Salzburg)
Previous UEFA Cup/Europa League best: runners-up (1997/98)
Sevilla (ESP)
UEFA ranking: 8
Domestic position: 2
Group stage: W4 D0 L2 F18 A6
Last season: UEFA Champions League quarter-finals (lost 2-1 v Bayern München)
Previous UEFA Cup/Europa League best: winners (2015/16*, 2014/15, 2013/14, 2006/07, 2005/06)
BATE Borisov v Arsenal
BATE Borisov (BLR)
UEFA ranking: 57
Domestic position: 1 (summer season)
Group stage: W3 D0 L3 F9 A9
Last season: UEFA Europa League group stage
Previous UEFA Cup/Europa League best: round of 32 (2018/19, 2012/13*, 2010/11)
Arsenal (ENG)
UEFA ranking: 10
Domestic position: 6
Group stage: W5 D1 L0 F12 A2
Last season: UEFA Europa League semi-finals (lost 2-1 v Atlético Madrid)
Previous UEFA Cup/Europa League best: runners-up (1999/2000*)
Malmö v Chelsea
Malmö (SWE)
UEFA ranking: 72
Domestic position: 3 (summer season)
Group stage: W2 D3 L1 F7 A6
Last season: UEFA Champions League second qualifying round (lost 4-2 v Vardar)
Previous UEFA Cup/Europa League best: round of 32 (2018/19)
Chelsea (ENG)
UEFA ranking: 18
Domestic position: 4
Group stage: W5 D1 L0 F12 A3
Last season: UEFA Champions League round of 16 (lost 4-1 v Barcelona)
Previous UEFA Cup/Europa League best: winners (2012/13*)
Fenerbahçe v Zenit
Fenerbahçe (TUR)
UEFA ranking: 47
Domestic position: 17
Group stage: W2 D2 L2 F7 A7
Last season: UEFA Europa League play-offs (lost 4-1 v Vardar)
Previous UEFA Cup/Europa League best: semi-finals (2012/13)
Zenit (RUS)
UEFA ranking: 17
Domestic position: 1
Group stage: W3 D2 L1 F6 A5
Last season: UEFA Europa League round of 16 (lost 3-2 v RB Leipzig)
Previous UEFA Cup/Europa League best: winners (2007/08)
Galatasaray v Benfica
Galatasaray (TUR)*
UEFA ranking: 70
Domestic position: 5
Group stage: W1 D1 L4 F5 A8
Last season: UEFA Europa League second qualifying round (lost 3-1 v Östersunds)
Previous UEFA Cup/Europa League best: winners (1999/2000)
Benfica (POR)*
UEFA ranking: 26
Domestic position: 4
Group stage: W2 D1 L3 F6 A11
Last season: UEFA Champions League group stage
Previous UEFA Cup/Europa League best: runners-up (2013/14*, 2012/13*, 1982/83)
Rapid Wien v Internazionale
Rapid Wien (AUT)
UEFA ranking: 63
Domestic position: 8
Group stage: W3 D1 L2 F6 A9
Last season: not in Europe
Previous UEFA Cup/Europa League best: round of 32 (2015/16)
Internazionale Milano (ITA)*
UEFA ranking: 55
Domestic position: 3
Group stage: W2 D2 L2 F6 A7
Last season: not in Europe
Previous UEFA Cup/Europa League best: winners (1990/91, 1993/94, 1997/98)
Club Brugge v Salzburg
Club Brugge (BEL)*
UEFA ranking: 38
Domestic position: 2
Group stage: W1 D3 L2 F6 A5
Last season: UEFA Europa League play-offs (lost 3-0 v AEK Athens)
Previous UEFA Cup/Europa League best: runners-up (1975/76)
Salzburg (AUT)
UEFA ranking: 30
Domestic position: 1
Group stage: W6 D0 L0 F17 A6
Last season: UEFA Europa League semi-finals (lost 3-2 v Marseille)
Previous UEFA Cup/Europa League best: runners-up (1993/94)
Slavia Praha v Genk
Slavia Praha (CZE)
UEFA ranking: 90
Domestic position: 1
Group stage: W3 D1 L2 F4 A3
Last season: UEFA Europa League group stage
Previous UEFA Cup/Europa League best: semi-finals (1995/96)
Genk (BEL)
ranking: 61
Domestic position: 1
Group stage: W3 D2 L1 F14 A8
Last season: not in Europe
Previous UEFA Cup/Europa League best: quarter-finals (2016/17)
Krasnodar v Leverkusen
Krasnodar (RUS)
UEFA ranking: 42
Domestic position: 2
Group stage: W4 D0 L2 F8 A8
Last season: UEFA Europa League play-offs (lost on away goals v Crvena zvezda)
Previous UEFA Cup/Europa League best: round of 16 (2016/17)
Leverkusen (GER)
UEFA ranking: 28
Domestic position: 11
Group stage: W4 D1 L1 F16 A9
Last season: not in Europe
Previous UEFA Cup/Europa League best: winners (1987/88)
Zürich v Napoli
Zürich (SUI)
UEFA ranking: 78
Domestic position: 4
Group stage: W3 D1 L2 F7 A6
Last season: not in Europe
Previous UEFA Cup/Europa League best: round of 16 (1998/99, 1982/83)
Napoli (ITA)*
UEFA ranking: 16
Domestic position: 2
Group stage: W2 D3 L1 F7 A5
Last season: UEFA Europa League round of 32* (lost on away goals v RB Leipzig)
Previous UEFA Cup/Europa League best: winners (1988/89)
Shakhtar v Frankfurt
Shakhtar Donetsk (UKR)*
UEFA ranking: 13
Domestic position: 1
Group stage: W1 D3 L2 F8 A16
Last season: UEFA Champions League round of 16 (lost on away goals v Roma)
Previous UEFA Cup/Europa League best: winners (2008/09*)
Eintracht Frankfurt (GER)
UEFA ranking: 97
Domestic position: 5
Group stage: W6 D0 L0 F17 A5
Last season: not in Europe
Previous UEFA Cup/Europa League best: winners (1979/80)
Celtic v Valencia
Celtic (SCO)
UEFA ranking: 44
Domestic position: 3
Group stage: W3 D0 L3 F6 A8
Last season: UEFA Europa League round of 32* (lost 3-1 v Zenit)
Previous UEFA Cup/Europa League best: runners-up (2002/03)
Valencia (ESP)*
UEFA ranking: 60
Domestic position: 14
Group stage: W2 D2 L2 F6 A6
Last season: not in Europe
Previous UEFA Cup/Europa League best: winners (2003/04)
Rennes v Real Betis
Rennes (FRA)
UEFA ranking: 112
Domestic position: 11
Group stage: W3 D0 L3 F7 A8
Last season: not in Europe
Previous UEFA Cup/Europa League best: round of 32 (2018/19)
Real Betis (ESP)
UEFA ranking: 73
Domestic position: 5
Group stage: W3 D3 L0 F7 A2
Last season: not in Europe
Previous UEFA Cup/Europa League best: round of 16 (2013/14, 2005/06*, 1998/99, 1995/96)
Olympiacos v Dynamo Kyiv
Olympiacos (GRE)
UEFA ranking: 35
Domestic position: 2
Group stage: W3 D1 L2 F11 A6
Last season: UEFA Champions League group stage
Previous UEFA Cup/Europa League best: round of 16 (2016/17, 2011/12*, 2004/05*, 1989/90)
Dynamo Kyiv (UKR)
UEFA ranking: 21
Domestic position: 4
Group stage: W3 D2 L1 F10 A7
Last season: UEFA Europa League round of 16 (lost 4-2 v Lazio)
Previous UEFA Cup/Europa League best: semi-finals (2008/09*)
Viktoria Plzeň v Dinamo Zagreb
Viktoria Plzeň (CZE)*
UEFA ranking: 43
Domestic position: 2
Group stage: W2 D1 L3 F7 A16
Last season: UEFA Europa League round of 16 (lost 3-2aet v Sporting CP)
Previous UEFA Cup/Europa League best: round of 16 (2017/18, 2013/14*, 2012/13)
Dinamo Zagreb (CRO)
UEFA ranking: 56
Domestic position: 4
Group stage: W4 D2 L0 F11 A3
Last season: UEFA Europa League play-offs (lost on away goals v Skënderbeu)
Previous UEFA Cup/Europa League best: round of 16 (1997/98)
Sporting CP v Villarreal
Sporting CP (POR)
UEFA ranking: 31
Domestic position: 2
Group stage: W4 D1 L1 F13 A3
Last season: UEFA Europa League quarter-finals* (lost 2-1 v Atlético Madrid)
Previous UEFA Cup/Europa League best: runners-up (2004/05)
Villarreal (ESP)
UEFA ranking: 27
Domestic position: 17
Group stage: W2 D4 L0 F12 A5
Last season: UEFA Europa League round of 32 (lost 4-1 v Lyon)
Previous UEFA Cup/Europa League best: semi-finals (2015/16, 2010/11, 2003/04)
* Via UEFA Champions League group stage
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